This is the leading pharmacology reference since 1941. Throughout its 60 year history, “Goodman and Gilman’s” careful balance of basic science and clinical application has guided practitioners to a clear understanding of the drugs most useful in preventing, diagnosing and treating disease. It details how and why drugs affect different body systems, the chemical properties of drugs, dosage information, drug interactions and toxic effects. Well organised, extensively indexed, rigorously peer reviewed and referenced to the most up-to-date literature in the field, “Goodman and Gilman’s” is the definitive resource on therapeutics. It provides coverage of the general principles of pharmacology, including pharmacokinetics and pharmacodynamics, the principles of therapeutics, and the principles of toxicology and gene based therapy.